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Joint Institute for Nuclear Research
11.11.2026

Viktor Kokhan "Radiotherapy for Neurodegenerative Diseases: Current Status and Prospects"

The report presents the results of studying the effects of combined ionizing radiation (γ-rays and high-energy 12С nuclei) on the progression of neurodegenerative diseases. The study was conducted using a transgenic model that replicates the pathophysiological and clinical features of severe tauopathies: Tau P301S mice.

The speaker will discuss the radiation-induced behavioral benefits observed at both the early and late stages of pathology, as well as the accompanying biochemical and molecular alterations.

Furthermore, several working hypotheses will be proposed to explain the mechanisms behind the observed neuroprotective effects of combined radiotherapy. During the discussion, participants will have the opportunity to consider the potential clinical translation of  these findings and the prospects of utilizing radiotherapy as a tool for treating severe neurodegenerative diseases of the central nervous system.

Presentation

Link to watch the video on the JINR resource:
https://disk.jinr.ru/index.php/s/LLDEKQWPq9kiAMF

Link to watch the video on VK:
https://vkvideo.ru/video-179241683_456239906