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Genetic effect of ionizing radiation on generative cells (gametes) is characterized not only by a diversity of observed changes in individual genes and the genome as a whole but also by the danger that these changes constitute for the coming generations.


The observed diversity stems from both the features of the DNA organization of the nanotarget (gene) and the microtarget (genome) and the character of the ionizing particle energy distribution in these targets. The topics covered at the seminar were modern concepts of the gene and genome DNA organization, energy distribution in the genome (within the modern track structure theory), and the spectrum of primary (theoretically expected0 and observed (from the sequence analysis of radiation-induced mutations) inherited DNA changes.

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